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Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B(−/−) mice

Some autistic individuals exhibit abnormal development of the caudate nucleus and associative cortical areas, suggesting potential dysfunction of cortico-basal ganglia (BG) circuits. Using optogenetic and electrophysiological approaches in mice we identified a narrow postnatal period characterized b...

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Bibliografiske detaljer
Udgivet i:Nat Neurosci
Main Authors: Peixoto, Rui T., Wang, Wengang, Croney, Donyell M., Kozorovitskiy, Yevgenia, Sabatini, Bernardo L.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846490/
https://ncbi.nlm.nih.gov/pubmed/26928064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4260
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