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Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B(−/−) mice

Some autistic individuals exhibit abnormal development of the caudate nucleus and associative cortical areas, suggesting potential dysfunction of cortico-basal ganglia (BG) circuits. Using optogenetic and electrophysiological approaches in mice we identified a narrow postnatal period characterized b...

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Bibliografiska uppgifter
I publikationen:Nat Neurosci
Huvudupphovsmän: Peixoto, Rui T., Wang, Wengang, Croney, Donyell M., Kozorovitskiy, Yevgenia, Sabatini, Bernardo L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846490/
https://ncbi.nlm.nih.gov/pubmed/26928064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4260
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