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Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b-AP15
The ubiquitin–proteasome system (UPS) is increasingly recognized as a therapeutic target for the development of anticancer therapies. The success of the 20S proteasome core particle (20S CP) inhibitor bortezomib in the clinical management of multiple myeloma has raised the possibility of identifying...
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| Veröffentlicht in: | Chem Biol Drug Des |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846425/ https://ncbi.nlm.nih.gov/pubmed/25854145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12571 |
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