Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death

When innate immune cells such as macrophages are challenged with environmental stresses or infection by pathogens, they trigger the rapid assembly of multi-protein complexes called inflammasomes that are responsible for initiating pro-inflammatory responses and a form of cell death termed pyroptosis...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sanman, Laura E, Qian, Yu, Eisele, Nicholas A, Ng, Tessie M, van der Linden, Wouter A, Monack, Denise M, Weerapana, Eranthie, Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846378/
https://ncbi.nlm.nih.gov/pubmed/27011353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13663
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