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Packaging HIV- or FIV-based Lentivector Expression Constructs & Transduction of VSV-G Pseudotyped Viral Particles

As with standard plasmid vectors, it is possible to transfect lentivectors in plasmid form into cells with low-to-medium efficiency to obtain transient expression of effectors. Packaging lentiviral expression constructs into pseudoviral particles, however, enables up to 100% transduction, even with...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Mendenhall, Amy, Lesnik, Jacob, Mukherjee, Chandreyee, Antes, Travis, Sengupta, Ranjita
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846333/
https://ncbi.nlm.nih.gov/pubmed/22508377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3171
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