Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities

The High Mobility Group A1 proteins (HMGA1) are nonhistone chromatinic proteins with a critical role in development and cancer. We have recently reported that HMGA1 proteins are able to increase the expression of spindle assembly checkpoint (SAC) genes, thus impairing SAC function and causing chromo...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Pierantoni, Giovanna Maria, Conte, Andrea, Rinaldo, Cinzia, Tornincasa, Mara, Gerlini, Raffaele, Valente, Davide, Izzo, Antonella, Fusco, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845974/
https://ncbi.nlm.nih.gov/pubmed/26889953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1146835
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