Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes

The mitotic spindle assembly checkpoint (SAC) is an essential control system of the cell cycle that contributes to mantain the genomic stability of eukaryotic cells. SAC genes expression is often deregulated in cancer cells, leading to checkpoint impairment and chromosome instability. The mechanisms...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Pierantoni, Giovanna Maria, Conte, Andrea, Rinaldo, Cinzia, Tornincasa, Mara, Gerlini, Raffaele, Federico, Antonella, Valente, Davide, Medico, Enzo, Fusco, Alfredo
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627312/
https://ncbi.nlm.nih.gov/pubmed/26009897
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