Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes

The mitotic spindle assembly checkpoint (SAC) is an essential control system of the cell cycle that contributes to mantain the genomic stability of eukaryotic cells. SAC genes expression is often deregulated in cancer cells, leading to checkpoint impairment and chromosome instability. The mechanisms...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Pierantoni, Giovanna Maria, Conte, Andrea, Rinaldo, Cinzia, Tornincasa, Mara, Gerlini, Raffaele, Federico, Antonella, Valente, Davide, Medico, Enzo, Fusco, Alfredo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627312/
https://ncbi.nlm.nih.gov/pubmed/26009897
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