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A bright future for protein kinase D1 as a drug target to prevent or treat pancreatic cancer

Pancreatic ductal adenocarcinoma originates from acinar cells that undergo acinar-to-ductal metaplasia (ADM). ADM is initiated in response to growth factors, inflammation, and oncogene activation and leads to a de-differentiated, duct-like phenotype. Our recent publication demonstrated a transformin...

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Vydáno v:Mol Cell Oncol
Hlavní autoři: Liou, Geou-Yarh, Storz, Peter, Leitges, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845192/
https://ncbi.nlm.nih.gov/pubmed/27308552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1035477
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