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Protein kinase D enzymes – novel kinase targets in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) is characterized by advanced stage desmoplastic tumors with a high prevalence of genetic abnormalities. Occurrence of PDA is linked to activating Kras mutations and aberrant epidermal growth factor receptor signaling, leading to additional activation of wildtyp...

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Pubblicato in:Expert Rev Gastroenterol Hepatol
Autori principali: Liou, Geou-Yarh, Storz, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832565/
https://ncbi.nlm.nih.gov/pubmed/26174103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17474124.2015.1069706
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