Patients with chronic lymphocytic leukaemia (CLL) differ in the pattern of CTLA-4 expression on CLL cells: the possible implications for immunotherapy with CTLA-4 blocking antibody

Recently, systemic administration of a human monoclonal antibody directed against cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on circulating T cells in patients with chronic lymphocytic leukaemia (CLL) has been considered. Also, CLL cells have been shown to express CTLA-4, increas...

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Bibliographic Details
Published in:Tumour Biol
Main Authors: Ciszak, Lidia, Frydecka, Irena, Wolowiec, Dariusz, Szteblich, Aleksandra, Kosmaczewska, Agata
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844645/
https://ncbi.nlm.nih.gov/pubmed/26490985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-015-4217-1
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