Exogenous IL-2 Controls the Balance in Th1, Th17, and Treg Cell Distribution in Patients with Progressive Rheumatoid Arthritis Treated with TNF-Alpha Inhibitors

Interleukin-2 (IL-2) has been suggested to control Treg/Th17 balance. Recently, we reported a relationship of rheumatoid arthritis (RA) activity/progression with irreversible systemic Treg and Th1 defects including serum IL-2 shortage. Herein, we explore the role of in vitro stimulation with rIL-2 i...

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Detalhes bibliográficos
Publicado no:Inflammation
Main Authors: Kosmaczewska, Agata, Ciszak, Lidia, Swierkot, Jerzy, Szteblich, Aleksandra, Kosciow, Katarzyna, Frydecka, Irena
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344954/
https://ncbi.nlm.nih.gov/pubmed/25145773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-014-9987-x
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