Dysregulated Expression of Both the Costimulatory CD28 and Inhibitory CTLA-4 Molecules in PB T Cells of Advanced Cervical Cancer Patients Suggests Systemic Immunosuppression Related to Disease Progression

Cervical cancer (CC) occurs more frequently in women who are immunosuppressed, suggesting that both local and systemic immune abnormalities may be involved in the evolution of the disease. Costimulatory CD28 and inhibitory CTLA-4 molecules expressed in T cells play a key role in the balanced immune...

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Autores principales: Kosmaczewska, Agata, Bocko, Dorota, Ciszak, Lidia, Wlodarska-Polinska, Iwona, Kornafel, Jan, Szteblich, Aleksandra, Masternak, Anna, Frydecka, Irena
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313031/
https://ncbi.nlm.nih.gov/pubmed/22094905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12253-011-9471-y
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