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Profiling serum bile acid glucuronides in humans: gender divergences, genetic determinants and response to fenofibrate
Glucuronidation, catalyzed by UDP-glucuronosyltransferase (UGT) enzymes detoxifies cholestatic bile acids (BAs). We aimed at i) characterizing the circulating BA-glucuronide (-G) pool composition in humans, ii) evaluating how sex and UGT polymorphisms influence this composition, and iii) analyzing t...
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| Izdano u: | Clin Pharmacol Ther |
|---|---|
| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844538/ https://ncbi.nlm.nih.gov/pubmed/23756370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.122 |
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