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Elucidating the Mechanism by which Compensatory Mutations Rescue an HIV-1 Matrix Mutant Defective for Gag Membrane Targeting and Envelope Glycoprotein Incorporation
The matrix (MA) domain of the HIV-1 Gag is responsible for Gag targeting to the plasma membrane where virions assemble. MA also plays a role in the incorporation of the viral envelope (Env) glycoproteins, and can influence particle infectivity post-maturation and post-entry. A highly basic region of...
Gorde:
| Argitaratua izan da: | J Mol Biol |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844178/ https://ncbi.nlm.nih.gov/pubmed/25659909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.01.018 |
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