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Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation–contraction coupling supramolecular complex

The protein mammalian target of rapamycin (mTOR) is a serine/threonine kinase regulating a number of biochemical pathways controlling cell growth. mTOR exists in two complexes termed mTORC1 and mTORC2. Regulatory associated protein of mTOR (raptor) is associated with mTORC1 and is essential for its...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Lopez, Rubén J., Mosca, Barbara, Treves, Susan, Maj, Marcin, Bergamelli, Leda, Calderon, Juan C., Bentzinger, C. Florian, Romanino, Klaas, Hall, Michael N., Rüegg, Markus A., Delbono, Osvaldo, Caputo, Carlo, Zorzato, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843809/
https://ncbi.nlm.nih.gov/pubmed/25431931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140935
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