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JP-45/JSRP1 variants affect skeletal muscle excitation contraction coupling by decreasing the sensitivity of the dihydropyridine receptor
JP-45 (also JP45; encoded by JSRP1) is an integral protein constituent of the skeletal muscle sarcoplasmic reticulum junctional face membrane interacting with Ca(v)1.1 (the α.1 subunit of the voltage sensing dihydropyridine receptor, DHPR) and the luminal calcium-binding protein calsequestrin. Two J...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519957/ https://ncbi.nlm.nih.gov/pubmed/22927026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22209 |
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