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JP-45/JSRP1 variants affect skeletal muscle excitation contraction coupling by decreasing the sensitivity of the dihydropyridine receptor

JP-45 (also JP45; encoded by JSRP1) is an integral protein constituent of the skeletal muscle sarcoplasmic reticulum junctional face membrane interacting with Ca(v)1.1 (the α.1 subunit of the voltage sensing dihydropyridine receptor, DHPR) and the luminal calcium-binding protein calsequestrin. Two J...

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Detaylı Bibliyografya
Asıl Yazarlar: Yasuda, Toshimichi, Delbono, Osvaldo, Wang, Zhong-Min, Messi, Maria L., Girard, Thierry, Urwyler, Albert, Treves, Susan, Zorzato, Francesco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519957/
https://ncbi.nlm.nih.gov/pubmed/22927026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22209
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