Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout mice

Muscle strength declines with age in part due to a decline of Ca(2+) release from sarcoplasmic reticulum calcium stores. Skeletal muscle dihydropyridine receptors (Ca(v)1.1) initiate muscle contraction by activating ryanodine receptors in the sarcoplasmic reticulum. Ca(v)1.1 channel activity is enha...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Mosca, Barbara, Delbono, Osvaldo, Messi, Maria Laura, Bergamelli, Leda, Wang, Zhong-Min, Vukcevic, Mirko, Lopez, Ruben, Treves, Susan, Nishi, Miyuki, Takeshima, Hiroshi, Paolini, Cecilia, Martini, Marta, Rispoli, Giorgio, Protasi, Feliciano, Zorzato, Francesco
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856057/
https://ncbi.nlm.nih.gov/pubmed/23443569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2496
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk