Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout mice

Muscle strength declines with age in part due to a decline of Ca(2+) release from sarcoplasmic reticulum calcium stores. Skeletal muscle dihydropyridine receptors (Ca(v)1.1) initiate muscle contraction by activating ryanodine receptors in the sarcoplasmic reticulum. Ca(v)1.1 channel activity is enha...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Mosca, Barbara, Delbono, Osvaldo, Messi, Maria Laura, Bergamelli, Leda, Wang, Zhong-Min, Vukcevic, Mirko, Lopez, Ruben, Treves, Susan, Nishi, Miyuki, Takeshima, Hiroshi, Paolini, Cecilia, Martini, Marta, Rispoli, Giorgio, Protasi, Feliciano, Zorzato, Francesco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856057/
https://ncbi.nlm.nih.gov/pubmed/23443569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2496
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