Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation–contraction coupling supramolecular complex

The protein mammalian target of rapamycin (mTOR) is a serine/threonine kinase regulating a number of biochemical pathways controlling cell growth. mTOR exists in two complexes termed mTORC1 and mTORC2. Regulatory associated protein of mTOR (raptor) is associated with mTORC1 and is essential for its...

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Pubblicato in:Biochem J
Autori principali: Lopez, Rubén J., Mosca, Barbara, Treves, Susan, Maj, Marcin, Bergamelli, Leda, Calderon, Juan C., Bentzinger, C. Florian, Romanino, Klaas, Hall, Michael N., Rüegg, Markus A., Delbono, Osvaldo, Caputo, Carlo, Zorzato, Francesco
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843809/
https://ncbi.nlm.nih.gov/pubmed/25431931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140935
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