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Efficient Synthesis of Nicotinamide-1-(15)N for Ultrafast NMR Hyperpolarization Using Parahydrogen
[Image: see text] Nicotinamide (a vitamin B(3) amide) is one of the key vitamins as well as a drug for treatment of M. tuberculosis, HIV, cancer, and other diseases. Here, an improved Zincke reaction methodology is presented allowing for straightforward and scalable synthesis of nicotinamide-1-(15)N...
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| Publicat a: | Bioconjug Chem |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2016
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843783/ https://ncbi.nlm.nih.gov/pubmed/26999571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00148 |
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