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Toward hyperpolarized molecular imaging of HIV: synthesis and longitudinal relaxation properties of (15)N-Azidothymidine
Previously unreported (15)N labeled Azidothymidine (AZT) was prepared as an equimolar mixture of two isotopomers: 1-(15)N-AZT and 3-(15)N-AZT. Polarization decay of (15)N NMR signal was studied in high (9.4 T) and low (~50 mT) magnetic fields. (15)N T(1) values were 45 ± 5 s (1-(15)N-AZT) and 37 ± 2...
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| Publicado no: | J Labelled Comp Radiopharm |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287256/ https://ncbi.nlm.nih.gov/pubmed/25156931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3220 |
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