High-dose perioperative atorvastatin and acute kidney injury following cardiac surgery: a randomized clinical trial

IMPORTANCE: Hydroxy-methylglutaryl-coenzyme A reductase inhibitors affect several mechanisms underlying acute kidney injury (AKI). OBJECTIVE: To test the hypothesis that short-term high-dose perioperative atorvastatin would reduce AKI following cardiac surgery DESIGN, SETTING, PARTICIPANTS: Double-b...

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Veröffentlicht in:JAMA
Hauptverfasser: Billings, Frederic T., Hendricks, Patricia A., Schildcrout, Jonathan S., Shi, Yaping, Petracek, Michael R., Byrne, John G., Brown, Nancy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843765/
https://ncbi.nlm.nih.gov/pubmed/26906014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2016.0548
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