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Heme Oxygenase-1 and Acute Kidney Injury following Cardiac Surgery

BACKGROUND: Intraoperative hemolysis and inflammation are associated with acute kidney injury (AKI) following cardiac surgery. Plasma-free hemoglobin induces heme oxygenase-1 (HO-1) expression. HO-1 degrades heme but increases in experimental models of AKI. This study tested the hypothesis that plas...

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Detalhes bibliográficos
Main Authors: Billings, Frederic T., Yu, Chang, Byrne, John G., Petracek, Michael R., Pretorius, Mias
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024967/
https://ncbi.nlm.nih.gov/pubmed/24847330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357871
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