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High-dose perioperative atorvastatin and acute kidney injury following cardiac surgery: a randomized clinical trial
IMPORTANCE: Hydroxy-methylglutaryl-coenzyme A reductase inhibitors affect several mechanisms underlying acute kidney injury (AKI). OBJECTIVE: To test the hypothesis that short-term high-dose perioperative atorvastatin would reduce AKI following cardiac surgery DESIGN, SETTING, PARTICIPANTS: Double-b...
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| Udgivet i: | JAMA |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843765/ https://ncbi.nlm.nih.gov/pubmed/26906014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2016.0548 |
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