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Simultaneous single-molecule epigenetic imaging of DNA methylation and hydroxymethylation
The modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are the two major DNA epigenetic modifications in mammalian genomes and play crucial roles in development and pathogenesis. Little is known about the colocalization or potential correlation of these two modifications. Here w...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843451/ https://ncbi.nlm.nih.gov/pubmed/27035984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600223113 |
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