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Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response

Nuclear factor kappa B (NF-κB) is an inducible transcription factor that plays critical roles in immune and stress responses and is often implicated in pathologies, including chronic inflammation and cancer. Although much has been learned about NF-κB–activating pathways, the specific repression of N...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Reintjes, Anja, Fuchs, Julian E., Kremser, Leopold, Lindner, Herbert H., Liedl, Klaus R., Huber, Lukas A., Valovka, Taras
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843428/
https://ncbi.nlm.nih.gov/pubmed/27051065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522372113
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