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Kaempferol stimulates gene expression of low-density lipoprotein receptor through activation of Sp1 in cultured hepatocytes

A high level of plasma low-density lipoprotein (LDL) cholesterol is considered a risk factor for atherosclerosis. Because the hepatic LDL receptor (LDLR) is essential for clearing plasma LDL cholesterol, activation of LDLR is a promising therapeutic target for patients with atherosclerotic disease....

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ochiai, Ayasa, Miyata, Shingo, Iwase, Masamori, Shimizu, Makoto, Inoue, Jun, Sato, Ryuichiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842988/
https://ncbi.nlm.nih.gov/pubmed/27109240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24940
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