Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain.

The putative channel-forming MII domains of the nicotinic, gamma-aminobutyric acid type A, and glycine receptors contain a highly conserved leucine residue. Mutation of this hydrophobic amino acid in the neuronal nicotinic receptor alpha 7 (Leu-247), reconstituted in Xenopus oocytes, modifies the io...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bertrand, D, Devillers-Thiéry, A, Revah, F, Galzi, J L, Hussy, N, Mulle, C, Bertrand, S, Ballivet, M, Changeux, J P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.4.1261
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