AB007. Neurotensin derived from cancer stroma contributes to castration resistance via promoting neuroendocrine transdifferentiation

The mechanism of neuroendocrine transdifferentiation (NED) during the development of castration-resistant prostate cancer (CRPC) remains undefined. Although androgen-deprivation therapy (ADT) can impair tumor cell growth, ADT can also triggers a parallel reaction, leading to increased neurotensin (N...

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Bibliographische Detailangaben
Veröffentlicht in:Transl Androl Urol
Hauptverfasser: Zhu, Shimiao, Shang, Zhiqun, Tian, Hao, Flores-Morales, Amilcar, Niu, Yuanjie
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2016
Schlagworte:
Plenary Session
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842563/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s007
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