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AB007. Neurotensin derived from cancer stroma contributes to castration resistance via promoting neuroendocrine transdifferentiation

The mechanism of neuroendocrine transdifferentiation (NED) during the development of castration-resistant prostate cancer (CRPC) remains undefined. Although androgen-deprivation therapy (ADT) can impair tumor cell growth, ADT can also triggers a parallel reaction, leading to increased neurotensin (N...

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Detalhes bibliográficos
Publicado no:Transl Androl Urol
Main Authors: Zhu, Shimiao, Shang, Zhiqun, Tian, Hao, Flores-Morales, Amilcar, Niu, Yuanjie
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842563/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s007
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