AB127. Synthetic Tet-inducible small hairpin RNAs targeting hTERT or Bcl-2 inhibit malignant phenotypes of bladder cancer T24 and 5637 cell

OBJECTIVE: To develop Tet-regulated small hairpin RNA (shRNA) that inhibits the malignant phenotypes of tumor cell through Ribonucleic acid interference (RNAi). METHODS: Here we build a type of tetracycline (Tet)-inducible vectors which can achieve regulatable expression of shRNA in a time-dependent...

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Publicat a:Transl Androl Urol
Autors principals: Liu, Yuchen, Lin, Junhao, Huang, Weiren, Cai, Zhiming
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842556/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s127
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