Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells

We previously reported that co-expression of the Gi-coupled metabotropic glutamate receptor 2 (mGlu(2)R) and the Gq-coupled serotonin (5-HT) 2A receptor (2AR) in Xenopus oocytes (Fribourg et al., 2011) results in inverse cross-signaling, where for either receptor, strong agonists suppress and invers...

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Dettagli Bibliografici
Pubblicato in:Pflugers Arch
Autori principali: Baki, Lia, Fribourg, Miguel, Younkin, Jason, Eltit, Jose Miguel, Moreno, Jose L., Park, Gyu, Vysotskaya, Zhanna, Narahari, Adishesh, Sealfon, Stuart C., Gonzalez-Maeso, Javier, Logothetis, Diomedes E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842341/
https://ncbi.nlm.nih.gov/pubmed/26780666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-015-1780-7
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