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Intracochlear drug injections through the round window membrane: Measures to improve drug retention

The goal of this study was to develop appropriate methodology to apply drugs quantitatively to perilymph of the ear. Intratympanic applications of drugs to the inner ear often result in variable drug levels in perilymph and can only be used for molecules that readily permeate the round window (RW) m...

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Pubblicato in:Audiol Neurootol
Autori principali: Plontke, Stefan K., Hartsock, Jared J., Gill, Ruth M., Salt, Alec N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842307/
https://ncbi.nlm.nih.gov/pubmed/26905306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000442514
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