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Round Window Membrane Intracochlear Drug Delivery Enhanced by Induced Advection

Delivery of therapeutic compounds to the inner ear via absorption through the round window membrane (RWM) has advantages over direct intracochlear infusions; specifically, minimizing impact upon functional hearing measures. However, previous reports show that significant basal-to-apical concentratio...

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Bibliografiske detaljer
Main Authors: Borkholder, David A., Zhu, Xiaoxia, Frisina, Robert D.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925065/
https://ncbi.nlm.nih.gov/pubmed/24291333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.11.021
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