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Murine Intracochlear Drug Delivery: Reducing Concentration Gradients within the Cochlea

Direct delivery of compounds to the mammalian inner ear is most commonly achieved by absorption or direct injection through the round window membrane (RWM), or infusion through a basal turn cochleostomy. These methods provide direct access to cochlear structures, but with a strong basal-to-apical co...

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Detalhes bibliográficos
Main Authors: Borkholder, David A., Zhu, Xiaoxia, Hyatt, Brad T., Archilla, Alfredo S., Livingston, William J., Frisina, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933796/
https://ncbi.nlm.nih.gov/pubmed/20451593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2010.04.014
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