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Murine Intracochlear Drug Delivery: Reducing Concentration Gradients within the Cochlea

Direct delivery of compounds to the mammalian inner ear is most commonly achieved by absorption or direct injection through the round window membrane (RWM), or infusion through a basal turn cochleostomy. These methods provide direct access to cochlear structures, but with a strong basal-to-apical co...

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Main Authors: Borkholder, David A., Zhu, Xiaoxia, Hyatt, Brad T., Archilla, Alfredo S., Livingston, William J., Frisina, Robert D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933796/
https://ncbi.nlm.nih.gov/pubmed/20451593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2010.04.014
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