Magnetic Targeted Delivery of Dexamethasone Acetate across the Round Window Membrane in Guinea Pigs

HYPOTHESIS: Magnetically susceptible PLGA nanoparticles will effectively target the round window membrane (RWM) for delivery of dexamethasone-acetate (Dex-Ac) to the scala tympani. BACKGROUND: Targeted delivery of therapeutics to specific tissues can be accomplished using different targeting mechani...

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Hlavní autoři: Du, Xiaoping, Chen, Kejian, Kuriyavar, Satish, Kopke, Richard D., Grady, Brian P., Bourne, David H., Li, Wei, Dormer, Kenneth J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522431/
https://ncbi.nlm.nih.gov/pubmed/23187928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0b013e318277a40e
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