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Permeability of the Round Window Membrane is Influenced by the Composition of Applied Drug Solutions and by Common Surgical Procedures

INTRODUCTION: Intratympanic drug delivery has become widely used in the clinic but little is known about how clinically-utilized drug preparations affect round window membrane permeability or how much drug is actually delivered to the cochlea. This study evaluated the effect of clinically relevant c...

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Detalhes bibliográficos
Main Authors: Mikulec, Anthony A., Hartsock, Jared J., Salt, Alec N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596477/
https://ncbi.nlm.nih.gov/pubmed/18758387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0b013e31818658ea
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