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p19(Arf) limits primary vitreous cell proliferation driven by PDGF-B

Arf encodes an important tumor suppressor, p19(Arf), which also plays a critical role to control hyperplasia in the primary vitreous during mouse eye development. In the absence of Arf, mice are born blind and display a phenotype closely mimicking severe forms of the human eye disease, persistent hy...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Iqbal, Nida S., Devitt, Caitlin C., Sung, Caroline Y., Skapek, Stephen X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842104/
https://ncbi.nlm.nih.gov/pubmed/26778750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.01.004
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