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miR-34a is essential for p19(Arf)-driven cell cycle arrest

The Arf tumor suppressor gene product, p19(Arf), regulates cell proliferation in incipient cancer cells and during embryo development. Beyond its commonly accepted p53-dependent actions, p19(Arf) also acts independently of p53 in both contexts. One such p53-independent effect with in vivo relevance...

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Detalhes bibliográficos
Main Authors: Iqbal, Nida, Mei, Jie, Liu, Jing, Skapek, Stephen X
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979915/
https://ncbi.nlm.nih.gov/pubmed/24401748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27725
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