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miR-34a is essential for p19(Arf)-driven cell cycle arrest
The Arf tumor suppressor gene product, p19(Arf), regulates cell proliferation in incipient cancer cells and during embryo development. Beyond its commonly accepted p53-dependent actions, p19(Arf) also acts independently of p53 in both contexts. One such p53-independent effect with in vivo relevance...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979915/ https://ncbi.nlm.nih.gov/pubmed/24401748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27725 |
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