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Pathogenesis of Persistent Hyperplastic Primary Vitreous in Mice Lacking the Arf Tumor Suppressor Gene

PURPOSE: Persistent hyperplastic primary vitreous (PHPV) is an idiopathic developmental eye disease associated with failed involution of the hyaloid vasculature. The present work addressed the pathogenesis of PHPV in a mouse model that replicates many aspects of the human disease. METHODS: Ophthalmo...

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Главные авторы: Martin, Amy C., Thornton, J. Derek, Liu, Jiewiu, Wang, XiaoFei, Zuo, Jian, Jablonski, Monica M., Chaum, Edward, Zindy, Frederique, Skapek, Stephen X.
Формат: Artigo
Язык:Inglês
Опубликовано: 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557705/
https://ncbi.nlm.nih.gov/pubmed/15452040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.04-0349
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