Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

The introduction of new therapies against particular genetic mutations in non-small-cell lung cancer is a promising avenue for improving patient survival, but the target population is small. There is a need to discover new potential actionable genetic lesions, to which end, non-conventional cancer p...

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Bibliographic Details
Published in:Oncogene
Main Authors: Anadón, C, Guil, S, Simó-Riudalbas, L, Moutinho, C, Setien, F, Martínez-Cardús, A, Moran, S, Villanueva, A, Calaf, M, Vidal, A, Lazo, P A, Zondervan, I, Savola, S, Kohno, T, Yokota, J, de Pouplana, L R, Esteller, M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842009/
https://ncbi.nlm.nih.gov/pubmed/26640150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.469
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