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Measurement of DNA mismatch repair activity in live cells

Loss of DNA mismatch repair (MMR) function leads to the development and progression of certain cancers. Currently, assays for DNA MMR activity involve the use of cell extracts and are technically challenging and costly. Here, we report a rapid, less labor-intensive method that can quantitatively mea...

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Detalhes bibliográficos
Main Authors: Lei, Xiufen, Zhu, Yong, Tomkinson, Alan, Sun, LuZhe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC484197/
https://ncbi.nlm.nih.gov/pubmed/15249596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh098
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