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Measurement of DNA mismatch repair activity in live cells

Loss of DNA mismatch repair (MMR) function leads to the development and progression of certain cancers. Currently, assays for DNA MMR activity involve the use of cell extracts and are technically challenging and costly. Here, we report a rapid, less labor-intensive method that can quantitatively mea...

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Autors principals: Lei, Xiufen, Zhu, Yong, Tomkinson, Alan, Sun, LuZhe
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC484197/
https://ncbi.nlm.nih.gov/pubmed/15249596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh098
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