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Detection and mapping of mismatched base pairs in DNA molecules by atomic force microscopy

Attempts were made to apply atomic force microscopy (AFM) imaging to the detection and mapping of the sites of base substitutions in DNA molecules. In essence, DNA fragments to be examined for possible base substitutions were mixed with an equal amount of a corresponding DNA standard and subjected t...

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Dettagli Bibliografici
Autori principali: Tanigawa, Masato, Gotoh, Masanori, Machida, Masayuki, Okada, Takao, Oishi, Michio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC103311/
https://ncbi.nlm.nih.gov/pubmed/10756205
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