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Detection and mapping of mismatched base pairs in DNA molecules by atomic force microscopy

Attempts were made to apply atomic force microscopy (AFM) imaging to the detection and mapping of the sites of base substitutions in DNA molecules. In essence, DNA fragments to be examined for possible base substitutions were mixed with an equal amount of a corresponding DNA standard and subjected t...

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Autors principals: Tanigawa, Masato, Gotoh, Masanori, Machida, Masayuki, Okada, Takao, Oishi, Michio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC103311/
https://ncbi.nlm.nih.gov/pubmed/10756205
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