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Detection and mapping of mismatched base pairs in DNA molecules by atomic force microscopy

Attempts were made to apply atomic force microscopy (AFM) imaging to the detection and mapping of the sites of base substitutions in DNA molecules. In essence, DNA fragments to be examined for possible base substitutions were mixed with an equal amount of a corresponding DNA standard and subjected t...

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Detalhes bibliográficos
Main Authors: Tanigawa, Masato, Gotoh, Masanori, Machida, Masayuki, Okada, Takao, Oishi, Michio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103311/
https://ncbi.nlm.nih.gov/pubmed/10756205
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