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Lack of homologous sequence-specific DNA methylation in response to stable dsRNA expression in mouse oocytes

Double-stranded RNA (dsRNA) induces sequence-specific mRNA degradation in most eukaryotic organisms via a conserved pathway known as RNA interference (RNAi). Post-transcriptional gene silencing by RNAi is also connected with transcriptional silencing of cognate sequences. In plants, this transcripti...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Svoboda, Petr, Stein, Paula, Filipowicz, Witold, Schultz, Richard M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC484184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15247344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh697
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