A phage display selection of engrailed homeodomain mutants and the importance of residue Q50

Mutants of engrailed homeodomain (HD) that retain DNA-binding activity were isolated using a phage display selection. This selection was used to enrich for active DNA-binding clones from a complex library consisting of over a billion members. A more focused library of mutant homeodomains consisting...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Simon, Matthew D., Sato, Ken, Weiss, Gregory A., Shokat, Kevan M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
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Articles
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC484177/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15247345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh690
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