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Active repression of transcription by the engrailed homeodomain protein.

The Drosophila engrailed gene product (En) is a homeodomain-containing protein that contributes to segmental patterning. In transfection assays it acts as a transcriptional repressor. We show that En is an active repressor, blocking activation by mammalian and yeast activators that bind to sites som...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Jaynes, J B, O'Farrell, P H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1673924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07663.x
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