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Active repression of transcription by the engrailed homeodomain protein.

The Drosophila engrailed gene product (En) is a homeodomain-containing protein that contributes to segmental patterning. In transfection assays it acts as a transcriptional repressor. We show that En is an active repressor, blocking activation by mammalian and yeast activators that bind to sites som...

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Main Authors: Jaynes, J B, O'Farrell, P H
格式: Artigo
語言:Inglês
出版: 1991
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC452804/
https://ncbi.nlm.nih.gov/pubmed/1673924
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