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Transmembrane TNF-TNFR2 Impairs Th17 Differentiation by Promoting Il2 Expression
The double-edged sword nature by which IL-2 regulates autoimmunity and the unpredictable outcomes of anti-TNF therapy in autoimmunity highlight the importance for understanding how TNF regulates IL-2. Transmembrane (tm) TNF preferentially binds TNFR2 while soluble (s) TNF binds TNFR1. We have previo...
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| Publicado no: | J Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4841279/ https://ncbi.nlm.nih.gov/pubmed/26268655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500286 |
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