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TNFα Promotes Th17 Cell Differentiation through IL-6 and IL-1β Produced by Monocytes in Rheumatoid Arthritis

TNFα plays an important role in autoimmune pathogenesis and is the main therapeutic target of rheumatoid arthritis. However, its underlying mechanism is not completely understood. In this study, we described that Th17 cells were accumulated in synovial fluid, which was attributable to TNFα aberrantl...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Zheng, Yingxia, Sun, Lei, Jiang, Ting, Zhang, Dongqing, He, Dongyi, Nie, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243768/
https://ncbi.nlm.nih.gov/pubmed/25436214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/385352
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